When you (or loved ones) are taking prescription or over the counter medications…there is a lot you should be worried about, and a lot that your pharmacist may not be telling you.

Most people are aware, for example, that several medications taken together can sometimes cause harmful interactions. Most also know that drug allergies can pose significant hazards. (These are topics of other articles in this series). And, many people know that young children, elderly adults, pregnant women, nursing women, and severely debilitated people may all be at higher risk for adverse drug events.

But what most people don’t know is that a simple blood test can be one of the most important pieces of information in determining the correct dose of many medications…and the results of that test are almost never available to your pharmacist, especially if your pharmacist fills your prescription in a retail drugstore. (And, that’s a bummer.)

The test I’m talking about, of course, is the ’serum creatinine test’ (’SEAR-’em cree-AT-tuh-neen tehst’. It’s a difficult name to pronounce and a difficult test to understand…but one that you NEED to know about if you or loved ones are taking over-the-counter or prescription medications.)

A serum creatinine test gives a physician or pharmacist an estimate of kidney function.

Serum creatinine is the ‘bean counter’ of modern medicine… letting folks know if the beans (the kidneys) are working as well as they should.

Why is that important?

Well, kidney function is extremely important in determining the correct doses of many medications since the kidneys (along with the liver) assist in the removal of medications from the body.

Almost all medications (and/or their chemical by-products) are either removed by the liver, by the kidneys, or, in many cases, by both the kidneys and liver working together.

So, simply put, when the beans are not working well, many medications will accumulate in the body and increase the risk of drug side effects. And that’s an even bigger bummer. (The same is true for liver problems, and we will talk about that in another article in this series.)

As a result, patients with reduced kidney function often need LOWER doses of many medications.

So how does this all work?

Well, creatinine is a chemical that occurs and circulates naturally in the human body. It is the result of normal protein break-down. And, like many medications, creatinine is normally removed from the blood by the beans. So, when the kidneys are not working well, the level of creatinine circulating in the bloodstream will start to go up…just like the blood level of many medications.

Physicians and pharmacists are routinely and easily able to determine how much creatinine is in the blood with the results of a serum creatinine test. (This test is part of a very common panel of blood tests. And, if the serum creatinine is high, many drugs need to have a lower dose.) The normal value for serum creatinine is about 0.4 to 1.5 mg/dl…but that can vary a bit from lab to lab.

So remember: ‘kidneys no work…serum creatinine go UP’.

Now, serum creatinine is not the best measure of kidney function (there are other tests that are much more accurate), but results of the serum creatinine test are usually the most readily available…and cheapest…and are generally accurate enough for most purposes…so serum creatinine is the de facto standard for estimating kidney function…most of the time.

The gold standard test that doctors use for measuring kidney function is called ‘creatinine clearance’ (cree-AT-tuh-neeeen CLEAR-uhhh-nce) However, not many patients get this particular test because it is pretty darn inconvenient…and smelly. You have to collect all of your urine for 24 hours and keep it in the fridge. Not a lot of volunteers for this test…

Creatinine clearance is the volume of blood that the kidneys clear of creatinine in a given amount of time (and it is usually reported as milliliters per minute).

So, when kidney function decreases, creatinine clearance (the amount of blood that the kidneys are successfully ‘cleaning’) also decreases.

So remember: ‘kidneys no work…creatinine clearance go DOWN’. (Note: this is easy to remember because it is the exact opposite of what you were initially thinking, and the opposite of what happens with serum creatinine. Most of medicine is like this.)

Now for the super tricky part just for those gunning for an A. There is a way to ‘guestimate’ creatinine clearance using serum creatinine…isn’t that neat. And, that’s probably the best way to determine renal function if a measured creatinine clearance is not available.

What you do is run the serum creatinine value through a fancy equation that will give you an estimated creatinine clearance, which is itself an estimate of kidney function. (Estimates of estimates of estimates…that’s the kind of exacting science I live for.)

For adults, that equation is the famous ‘Cockcroft-Gault equation corrected for ideal body weight and gender’…the equation everyone loves to hate. The Cockcroft-Gault equation (presumably named after Drs. Cockcroft and Gault…or maybe just Dr. Cockroft-Gault, or maybe Lara Croft), is generally considered very reliable since it has never been well validated in young patients, old patients, thin patients, fat patients…basically all the patients it gets used on. So go figure. Double bonus points if you can remember this:

For men, creatinine clearance =

((140- Age) ‘ IBW) / (72 ‘ SCr)

For women, creatinine clearance =

((140- Age) ‘ IBW ‘ 0.85) / (72 ‘ SCr)

Where Age is in years, IBW is ideal body weight in kilograms, and SCr is serum creatinine in mg/dl.

Now once you run this a few times, you’ll find that creatinine clearance for young healthy people is about 100 ml/min (we’ll just leave off the ‘ml/min’ part from now on).

And, dead people have a creatinine clearance of about 0, depending on how healthy they are.

Everyone else falls somewhere in between.

(Now someone in the back of the room is saying, ‘I just ran this on myself and I have a creatinine clearance of 150′. Well aren’t you special? In fact, young good-looking people can have creatinine clearances of 130, 140, or more…but it doesn’t do a whole lot of good since 100 is perfectly acceptable. In fact, it’s just another case of overachiever overkill.)

Now, if someone has a creatinine clearance of 80, that means that they have about…80% kidney function.

And, if someone has a creatinine clearance of 50, that means that they have about…50% kidney function. (Are you following all of this?)

Many drugs that are eliminated by the kidney will require moderate dosage reductions once a patient’s renal function is in the 40-60 range.

Patients in the 20-40 range will typically require very large reductions in dose.

And, patients who are in the ‘less than 20′ range will often need HUGE dosage reductions for medications eliminated by the kidney (or better yet, they’ll need to take medications that are removed by some other organ altogether…if such an alternative is available).

One last tidbit to consider. Renal function declines as people age. No getting around that. But, the rate of decline is different for different people. By the time you’re 50 years old, there is a reasonable chance you’ll have moderate renal function (or worse)…by the time you’re 80, you’ll almost certainly have some important degree of renal impairment… and you probably won’t even know it or feel it.

Now that you know more renal physiology than you ever, EVER wanted to know…let’s get back to the main thread of this article…medication safety.

If you (or a loved one) are at risk for having decreased kidney function (and I’ll tell you who such folks are in just a second), you need to step up to the plate and get a handle on this issue (because there is a very good chance that your physician and pharmacist either didn’t have renal function data or didn’t consider it when coming up with a dosage for you).

Here are the steps I recommend for everyone taking prescription or over-the-counter medications:

1) For everyone: If you have access to the results of a recent serum creatinine test (it is probably part of your annual physical and you may have gotten a copy), memorize it or write it down and then say to your physician or pharmacist when you get a medication, ‘Say, I think my serum creatinine is about X. So, does this medication need any dosage adjustment in order to be safe for me?

2) If you are in one of the following categories, you should expect your physician and pharmacist to have considered your renal function before dosing a medication:

• known kidney disease;
• age greater than 50;
• history or heart attack, angina, stroke, or other artery blockages;
• history of diabetes (any type);
• history of high blood pressure;
• prior exposure to chemotherapy drugs;
• prior prolonged exposure to IV antibiotics;
• frequent use of pain medications (especially non-steroidal anti-inflammatory drugs, but others as well).

So you might say to your physician or pharmacist, ‘Is this drug removed by the kidney, because I have condition X that could decrease kidney function and I just want to be safe.’ If the drug is removed by the kidney, you might also ask the physician or pharmacist to tell you what your serum creatinine is…and if he or she does not have this information, a big red flag should be going up in your head.

3) If you are not in one of the categories in question 2 and you don’t have a serum creatinine available, don’t worry. You’re probably safe. But you may want to ask your physician if there is a serum creatinine in your chart and if so, what it is.

4) If you are on dialysis of any sort, serum creatinine is not all that useful for dosing medications. Just make sure your physician and pharmacist are aware that you are on dialysis and perhaps ask, ‘Now is this the usual dose for someone on dialysis?’

These are some of the steps I hope you will consider the next time you get a prescription or over-the-counter medication so you can be sure that that you (or your loved one) are getting the right dose.

Throughout time there have always been two opposing points of view as to how to maintain good health, or how to regain it after having lost it. This conflict has continued since ancient times …. and no doubt will continue well into the future.

One ’side’ believes good health is as a result of outside intervention… drugs, surgery etc. The other ’side’ believes that good health results from living in harmony with natural law… correct nutrition… cleanliness etc.

Both sides tended to be critical of the other… nothing much has changed over the ages.

Modern mainstream western medicine takes the ‘outside’ approach. However, in recent years the “inside” approach which has always been the underlying principle behind Chinese traditional medicine has gained much ground. The increase in the popularity of the ‘Inside’ approach is no doubt due to a combination of several factors:

• Known Prescription drug side effects
• Dissatisfaction of traditional mainstream medicine
• Increasing cases of medical ‘misadventure’. (Hospitals are places to stay away from.)
• Awareness that good health is primarily a personal responsibility… not of overworked physicians.
• An increasing awareness that the medical industry is highly influenced by drug companies and that there are often better, safer and more economic natural alternatives to drugs.
• Major Drug recalls have evidenced that many potential prescription drug side effects are not known …. and may never be

In spite of this justified ’swing’ away from mainstream medicine and the growing importance of prescription drug side effects, mainstream medicine does have a place in everyone’s health program … part from the obvious ones in treating accident cases or chronic urgent illness. So, if you are already a proponent of the “inside” approach don’t overlook the benefits that mainstream medicine can offer to you in your overall quest for good health and longevity. These benefits are primarily in the early detection of a pending disease that you may not as yet be aware of!

Prescription drug side effects: A potential conflict

Let’s say your tests show that your cholesterol is ‘out of whack’, your ‘mainstream’ physician may first propose lowering your intake of diet cholesterol. That’s unlikely to be successful as ingested cholesterol only makes up a relatively small percentage of blood cholesterol.

They will next likely propose one of the cholesterol lowering drugs commonly known as “statins”. These are drugs that work by blocking an enzyme that your liver needs to manufacture cholesterol. (Up to 80% of your blood cholesterol is manufactured by your liver, NOT from the ingestion of cholesterol within your diet).

These drugs are very powerful and statin drug side effects are serious, including death. In fact Bayers were recently forced to withdraw their statin drug from the market place because of “unacceptable” levels of fatalities. In spite of such prescription drug side effects, sales of statin drugs amount to billions of dollars per year and are commonly prescribed.

It’s ironic that there are natural alternatives to these statin drugs which can assist in lowering cholesterol, and do it safely, and without side effects. But the general public hears very little about them as they are not patentable and there is not the financial incentive for the big corporate’s to promote them.

The same principle applies for many different ailments. There can be many legitimate methods of treatments. What is important is that you seek out the natural alternatives and apply them before agreeing to subject yourself to negative Prescription drug side effects.

Pharmaceutical drugs are “blockers” and do not normally heal the underlying ailment. They generally work by suppressing natural functions such as certain enzymes mentioned earlier when giving the “statin” example. Because of this process, results are often “instant” and as such there is sometimes a place for these powerful prescription drugs in the case of life threatening emergencies.

In contrast, natural products such as herbs, vitamins, etc. are “enablers”. They work at correcting the cause of the ailment which is often a nutrient deficiency of some sort. The results are not immediate and have to be measured in weeks, or even months.

If you have a serious ailment, work with your physician to try and correct it… by first using natural remedies. If she or he is not familiar with the treatment you would like to try, do some further research and get hold of supporting information so you are in a better position to discuss the options intelligently. If your physician has a closed mind to natural remedies it may be wise to ask around and find another qualified physician with an open mind. The consequences of prescription drug side effects are too serious.

Marc Deschamps is the editor of Health Longevity Magazine, a free online publication, featuring articles full of information on various health topics such as common diseases, immune support, cardiac, mental & sexual health plus appropriate solutions to help you find the road to health longevity.

We’ve all had garden variety headaches from time to time. Getting sleep, drinking water, or taking aspirin or Tylenol lets you squash these “tension headaches” (as doctors call them) quickly and easily.

But if you suffer from severe or chronic tension headaches, you know that headaches can take over your work and family life. A study by the American Headache Society shows that 70% of chronic headache sufferers have significant problems with daily functioning because of the headaches.

Migraine sufferers have symptoms in addition to headache; they may spend days each month in a darkened room because the pain and light-sensitivity are unbearable otherwise.

Fioricet: A New Option

Fioricet is one of the drugs that researchers have developed to manage headaches. It has been found to be effective for tension headaches. While studies haven’t shown it to be effective for migraine sufferers overall, some people with migraines seem to find it helpful as well.

Fioricet gets its effect from three different ingredients that attack different “parts” of your headache, just like a good laundry detergent has different ingredients to tackle grease, odors, and dirt.

So how does the dynamic trio work?

Fioricet has three parts, two of which may be old friends:

Butalbital
Acetominophen
Caffeine

Butalbital is a barbiturate; like other barbiturates, it has a relaxing effect. Butalbital will help you relax and make you feel a bit drowsy, which seems to help with tension headaches.

Acetominophen is a drug that you may recognize as the active ingredient in Tylenol. It can help with pain relief especially when combined with a relaxant.

Caffeine gives you the “buzz” that you may feel after drinking tea, coffee, or colas, or eating chocolate. Caffeine helps to reduce blood flow to the brain. Many scientists believe that “too much” blood flowing to the brain is part of what causes chronic tension headaches, so caffeine can reduce that effect.

Fioricet as part of your pain-management system

As headache sufferers, anything that might help get our lives back to normal sounds like a God-send. But there a couple of questions you should ask yourself before talking with your doctor about a prescription

? Do I have migraines? If you don’t know, talk about your symptoms with your doctor before deciding that Fioricet is a good fit for you.

? Is operating heavy machinery or doing a lot of driving part of my daily life? If you take a little too much Fioricet of if you’re very sensitive to barbiturates, it can create the feelings and behaviors of someone who has had too much alcohol. Being “drunk” is not a good mix with operating a crane or driving carloads of kids to school, soccer practice, and the library!

? Do I need a pain-killer at least once a day? Fioricet can make you dependent on it. Dependence can lead to “rebound headaches” (headaches as the drug leaves your system) and even more serious health consequences. Your doctor might suggest using Fioricet as a “back-up” medication - to use it for the days where your regular medication doesn’t work. And if you’ve previous experienced dependence on another drug (including alcohol), this medication is not for you.

I’ve Thought It Over, So What’s My Next Step?

Take the prescription to your local pharmacy or on-line drug store so it’s ready for your use at the sign of the first stubborn headache. Discussing any problems or side effects like dizziness or drowsiness with your doctor will help you manage this drug and can make it part of your plan for a pain-free life!

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Remember the last time you stubbed your toe? OUCH! It’s painful. But a stubbed toe usually doesn’t send us running to the medicine cabinet, since we know that the pain will pass within a few minutes.

But for more serious “acute” pain (pain that’s severe and constant for a couple of days), waiting it out may not be an option. For some acute pain, we might even make things worse: for example, if you hold a painful joint at an awkward angle to relieve the pain, you might end up with a muscle strain.

So what are our options? Sometimes simple over the counter medications may do the trick. But for when they don’t, a prescription medication may be the best bet.

UltraCET: Two Tough Drugs in one Small Pill

For acute pain from sprains, muscle strains, surgery, or dental work, or for arthritis flare-ups, UltraCET is a terrific option.

UltraCET is like any heroic dynamic duo (think Batman and Robin, or Xena and Gabrielle): One drug has the high-profile effect, but the other has an equally important, though less noticeable set of activities.

The “ultra” part of UltraCET is tramadol, the generic name for Ultram. Tramadol’s effect on your body is similar to the effect of narcotics (drugs like opium and heroin which are illegal, and codeine and morphine, which aren’t). Tramadol is just as good as narcotics in relieving pain but because unlike narcotics, it doesn’t affect your breathing or have other side-effects which stop us from regularly using medical narcotics.

The “CET” part of UltraCET is probably familiar to you in its day-to-day formulation; you might even have it in your medicine cabinet! It’s acetaminophen, the same drug that’s in Tylenol.

The two drugs work together (in “synergy”) to control pain. Acetaminophen helps “increase your threshold to pain.” That’s a fancy way of saying that mild pain signals from your body don’t even make it up to your brain so they don’t register. The bigger pain signals do make it to your brain, but that’s where tramadol kicks in - stopping the pain signals while they’re working their way through your brain. It’s just like Robin capturing the villain’s henchmen while Batman tackles the mastermind villain!

This Sounds Like The Perfect Rescue!

If you’ve just been seen by a doctor (a surgeon, or a dentist), she may well have already prescribed UltraCET for you. If you haven’t, but you’ve got a sprain or regular arthritis flares, you should talk with your doctor about a prescription for this drug.

Like anything powerful, though, you need to use it at the right time for the right reasons (letting Xena show off her acrobatic skills in a china shop is not a terrific idea!). The most important thing about taking UltraCET is to remember that it’s for short term use only!

Most doctors will suggest using it for up to five days only because you can otherwise become dependent on (addicted to) it. Stopping the drug after taking it a long time can cause severe withdrawal symptoms, so never take more than the doctor prescribes.

Your doctor will also ask you about other drugs that you’re taking. Tylenol, some antidepressants, and some seizure medications don’t mix with UltraCET. Neither does drinking, so you might wait to celebrate until after your sprain has healed!

Once these issues are resolved, your doctor can send you home with a prescription for UltraCET. It’ll help you get through the worst of the pain, and then best of all, it can ride off into the sunset when its job is done, leaving you to your pain-free life!

This must be a mistake! How could his drug costs rise from $150 a month to $1101 in just three weeks? My hands shook while I read the pharmacy bill.

There was no mistake. The bill I held recorded the drugs ordered by my fathers Alzheimers’ care unit. In only three weeks at this eldercare facility, his drug expenses had soared an incredible 734%. Ironically, his quality of life had plunged about the same percent. Walking and talking when he entered, he now spent his days confined to a wheelchair, unable to walk, drugged into a persistent stupor.

“I’ve got to do something.” The thought haunted me all day.

Then, that evening, an incidental trip to the grocery delivered the help I needed. It came in the form of a thick paperback book, The PDR Pocket Guide to Prescription Drugs (PDR Pocket Guide).

The PDR Pocket Guide provides tons of information for all prescription drugs on the market when it was printed. Specifics include:

• generic equivalents,
• why the drug is prescribed,
• how it should be taken,
• when it should not be taken,
• side effects and special warning, and
• possible interactions with other drugs and food.

The PDR Pocket Guide is available through Amazon.com, or you might find a copy like I did at your local grocery or bookstore. Jam-packed with almost 1700 pages of information, this paperback is a surprisingly affordable $6.99.

Using the pharmacy’s bill as a list of medications, I read the PDR report for each drug my father was using. What I found astonished me.

Two of fifteen drugs prescribed were being used “off-label” (not FDA approved for the condition it is used to treat). One of those was specifically contraindicated for use with Alzheimer’s patients. Two more were from drug families that I had previously identified as causing allergic reactions in my father.

When I was young, my father used to kid me by saying, “Up with this I will not put!” Up with this I wasn’t about to put either, so I called his doctor.

“My father is allergic to Furosemide.”

He bristled. “Where did you get an idea like that?”

“Furosemide is a sulfa drug. He’s allergic to sulfa drugs.”

“I never heard anything like that about Furosemide,” he barked. “Who told you that?”

“The PDR Pocket Guide.”

“Well, the PDR has a lot of stuff you don’t need to know.” His arrogance grated on my nerves.

“No more Furosemide.” Now I wasn’t asking, I was demanding. “You’ve seen his rash. He didn’t have it when he came to the care unit.”

“You’re not qualified to say what he should or should not have.”

“What am I doing,” I wondered, “arguing with a doctor who should be helping?” I wish I’d spoken the words I thought next. “Bye-bye! You’re fired!”

But, in that moment, I resolved to be fully in control of all my father’s drugs. I would learn everything I could and provide drugs direct to the facility. . .or not. There would be no more ordering drugs without my specific authorization

I enlisted the expertise of a pharmacist I found just down the street. She graciously took time from her crowded day to answer all my questions and explain anything I didn’t understand. She took a brief history of my father’s illness, made note of his allergies, and offered money-saving suggestions. She focused on providing excellent service. In short, she was, and is, an angel.

I immediately began to look for another physician to take over my father’s care, but I was too slow. Within a few weeks, my father died of complications from a massive insulin overdose.

Was my experience unusual? Probably not, according to a study from the Medical Expenditure Panel Survey (MEPS). On the subject of the increased cost of pharmaceuticals for people over-65, the study’s author, Marie Stagnitti, MPA, reports:

Every year from 1997-2000, the average out of pocket expense for prescription medicines for those with a purchase and age 65 and older was more than three times as high as the average out of pocket expense on prescription medicines for those with a purchase and under age 65.

The potential for overmedication in the elderly is clear in Stagnitti’s chart showing an average 23.5 prescriptions in both 1999 and 2000 for the over-65 group that used prescription drugs. The number of prescription drugs used by the under-65 group seemed high to me as well: 9.5 for 1999 and 10.1 prescriptions for the year 2000.

Overmedication is not only crushingly expensive for our elderly, it represents a real and present danger. You can do something about it. Please, learn about and oversee medications. You will help elders save money. You might even save a life.

The news has been full of the recent FDA findings on a new set of drugs to help relieve pain. These drugs have been approved for re-release, but it is unclear whether Vioxx will be available again and whether physicians will feel comfortable prescribing Celebrex and Bextra for many of their patients.

What happened to Celebrex and Vioxx?

Celebrex, Vioxx, and Bextra are all non-steroidal anti-inflammatory drugs (NSAIDs, pronounced en-said-z), similar to drugs like ibuprofen and naproxen, that are available over the counter (OTC). Celebrex, Vioxx and Bextra, (sometimes called Cox-2 inhibitors) however, use a slightly different method to achieve the same effect as their OTC cousins; this new method was supposed to limit the side effects some people experience on OTC drugs, including stomach and intestinal problems and allergic reactions. It was thought that because these drugs were less likely to cause such problems, they might be safer for patients with painful chronic conditions (like arthritis) to use for long periods of time.

Unfortunately, some studies of Cox-2 inhibitors suggest that while they don’t cause the sorts of side effects of other NSAIDs, they may create a greater risk of myocardial infarction (heart attack) or stroke. For people already at risk for these diseases (including those who have already experienced a stroke or heart problem), taking these drugs over the long run may significantly increase the risk of heart problems.

Now What Can I Do To Get Pain Relief?

Until a final decision has been made on each of these drugs, what can your healthcare provider do to help you with pain management? Here are important pieces of information to think about in determining what next steps to take:

* The Cox-2 inhibitors were not shown to be more effective than other NSAIDs, like naproxen. If you’ve been on or thinking about trying Vioxx or another Cox-2 inhibitor, you may be able to use an older anti-inflammatory drug. Naproxen, one of the older NSAIDs, may be an anti-inflammatory drug that actually lowers heart attack risk.

* Some people started on a Cox-2 inhibitors because they had a stomach ulcer or other risk factors for stomach or intestine bleeding (for example, people on blood thinners), which may be made worse by older anti-inflammatory drugs. For some people who are at risk for bleeding, other options like acetaminophen may be an option.

* There are lots of other medical options. Steroids can be used for shorter periods of time to manage inflammatory pain from diseases like arthritis and lupus. Opioids (drugs that resemble opium), such as oxycodone, codeine, and hydrocodone (Vicodin) can help with pain management, but they can have serious side effects, and some of them can be addictive, so working closely with your healthcare worker is key to determine if these will work for you. In addition, some antidepressants may help with chronic (long-term) pain, though the way this works isn’t yet known

* New procedures may be of assistance to you. Nerve block therapy (in which certain nerves are temporarily anaesthetized) can relieve pain temporarily. “Implantable “technologies, like spinal cord stimulation (SCS) systems and implantable drug delivery systems, do seem to help some people for whom other pain relief methods don’t work.

* If you aren’t getting the relief you need (with or without the use of Cox-2 inhibitors), you may want to consult a pain specialist. Some large hospitals (such as Stanford University) have departments devoted to pain management. The American Board of Pain Medicine and the PainConnection (at painconnection.org) can help you locate a pain specialist who can work with your other healthcare professionals to put a new treatment plan together for you.

Several methods are being used since time immemorial to cure the condition of hair loss. Hair loss is not just a male problem; it occurs in women too. Only that in women, it is not so very conspicuous. However, there are several treatment methods for both men as well as women. One such unisex treatment method is the hair loss treatment shampoo.

As the name suggests, this is a shampoo – a medicated shampoo, in fact – that is meant to be applied directly over the scalp, when having a bath. It does foam and lather like normal bath shampoos do, but the amount of lather is lesser than them. The shampoo is usually meant to be rubbed onto the scalp with the fingers and work it on slowly. Then it is to be kept on the scalp for a few minutes – five minutes are ideal – and then washed away with water. Cool water (not cold) shows better effects with these shampoos.

Today there are a lot of hair loss treatment shampoos available in the market. You will get one at your nearby drugstore. Or, you could get a prescribed one from a doctor. There are several brands on the Internet too, too many in fact, and deciding the one that would be good for your condition from among them is usually a pain. That is why, getting a hair loss treatment shampoo upon a doctor’s prescription is the best bet.

Most of the hair loss treatment shampoos are all herbal products, and these are very safe to use. At least, most of the genuine ones are! Generally, the herbal ingredients that these shampoos contain are aloe vera, saw palmetto, nettle, primrose oil, wheat extracts, carrot extracts, cucumber extracts, ginseng extracts, avocado extracts, rosemary, citric acid, etc. Several nutrients found in the food such as vitamin B3, vitamin E, vitamin C, vitamin A and several others are also added for extra effects from the shampoos.

There are also several synthetic shampoos available. These have ingredients like sodium laureth sulfate, cocamidopropyl betaine, methylparaben, propylparaben, butylparaben, phenoxyethanol,biotin, glycol stearate and hydrolyzed glycosaminogylacans among others. In all these shampoos, whether they are herbal or synthetic, the water used is always deionized pure water.

Of course, there are many shampoos – in fact most of them – that are a blend of herbal and synthetic products. Different companies have their own formulations too, and depending on the products used, these shampoos can bring additional benefits to the users such as shinier and silkier hair, hair that does not break, dandruff treatment, etc. In that way, other hair issues can also be addressed along with the use of the hair loss treatment shampoos. Because of their medical properties, these shampoos are always much more expensive than the normal shampoos that are available in the market.

If you are thinking of buying a hair loss treatment shampoo for yourself, the price should not be your first deciding factor. Look at the ingredients and study up a little on what they do for the hair. If that is too difficult for you, take a copy of the ingredients and ask your doctor. It is better to get a shampoo that works for you rather than paying good money for something that shows no results at the end of the day.

Are you spending a fortune on prescription arthritis medicines? Are they helping? Are you concerned about side effects? You may think a particular drug is a miraculous godsend. Yet, someone you know may take the same dose only to experience little relief and life-threatening side effects. All of the choices can be confusing.

The best treatment for your arthritis is based on your needs. Making the diagnosis of “osteoarthritis” is fairly straightforward, but deciding what to do about it is a complex and very individualized matter. There’s a wide range of options available to help you deal with OA; medicines are only part of the picture:

• The Basics: Weight Management / Exercise / Education / Modify Activities
• Medications: Pain Relievers, NSAIDs (like ibuprofen), Supplements
• Injections/ Bracing
• Surgery

The highest dose of the latest, “greatest” arthritis medicine on the market will NOT help unless you follow common-sense health practices. Focus on low-tech/low-cost habits that pay off throughout your body and quality of life. Modify the combination of remedies over your lifetime as symptoms wax and wane. Start simple, and then move to the next step if the first isn’t helping. You can cut back during the times you have less pain.

At this point, available medicines can relieve the symptoms of osteoarthritis, not cure it. There are some treatments for rheumatoid arthritis that can slow down joint destruction. Scientific research suggests that nutritional supplements, like glucosamine, might strengthen cartilage tissue. Stay tuned!

The dozens of arthritis medications available are categorized by drug class. The drug classes differ in the way your body handles the chemical that makes up the drug, known as the mechanism of action. Different mechanisms of action target different arthritis symptoms: pain vs. stiffness vs. inflammation. If you understand the classes, you will understand:

• how each drug works,
• which drugs are related because they work in a similar way,
• what side effects can occur, and
• why a drug may or may not be right for you.

Fortunately, there are eight drug classes to choose from to relieve your osteoarthritis symptoms. If you must avoid a whole class because you have another health condition, there are plenty of others that could keep you comfortable. Combining smaller doses from different classes may be the right answer. Usually only with prudent, thoughtful trials will you and your doctor discover what’s best for you. Keep a diary of the remedies you try, and their effects, good and bad. You spend a lot of money trying to feel better - don’t waste it!

Beware of your drugs’ true cost! “Cost” applies not only to the money you pay for the pills, but also to the toll they could take on your system in terms of side effects like stomach ulcers, kidney failure, addiction, and other problems worth avoiding!

OA is a chronic, degenerative condition that progresses at different rates in different patients (and even in different joints in the same body!) You’ve got better things to do than let OA rule your day. The right treatment strategy will get you back to the Pursuit of Happiness!

Want to learn more about all EIGHT classes of OA drugs? Visit to order “Making Sense of Arthritis Medicine: Manage Your Symptoms Safely” and discover relief that’s right for you!

If you are like many Americans, you are without health insurance. And the ranks of the uninsured are growing. According to the National Coalition on Health Care (NCHC), the number of uninsured was a record breaking 45 million in 2003. The growing number of uninsured is in large part being driven by individuals abandoning the corporate life to pursue their dreams as entrepreneurs and small business owners.

Unfortunately, this trend comes at a time when more and more medications are available to help treat the serious (and the not so serious) illnesses that many of us face today. But as you probably already know, without health insurance coverage, the prescription medications that you need are oftentimes too far out of reach; they are simply too expensive!

To make matters worse, most prescription medications cost far more in the United States than they do in other industrialized nations. These cost differences in conjunction with the fact that so many Americans do not have prescription medication coverage have spurred a national dialogue and heated debate. Despite these discussions, the needed regulatory changes have not materialized. Thus, the uninsured are left feeling that no affordable prescription coverage options exist.

Don’t Give Up Hope: There Are Options!

Fortunately, however, you are not without options. In fact, it is likely that you can afford the medications that you need. How, you ask, is this possible? Well, read on!

There are two primary ways you can afford or save money on your prescription medication. They include participating in one of the many (National, State, and Pharmaceutical) assistance programs and/or purchasing your medication from pharmacies located outside of the U.S.

Assistance Programs: Save From 25% to 100%!

Most persons are not aware that there are hundreds of programs available that provide either discounted or even free prescription medications to eligible US citizens. In fact, there are over thirty different national programs, virtually every state in the U.S. offers some sort of prescription medication assistance, and there are more than 250 different assistance programs offered by the many domestic and foreign pharmaceutical companies.

As you can probably guess, navigating the many programs to find the one that best fits your needs can be difficult. Each program has different eligibility requirements, application requirements, etc. However, the work required to take advantage of the program that best fits your needs will likely pay off. If you are eligible for assistance through one these programs, you can expect to save from 25% to 100% on the cost of your prescription medication. Savings like that are hard to ignore. And luckily, there are powerful tools available to help you find the program that is best for you.

Purchasing Your Medication from Pharmacies outside the US

Assuming that you don’t qualify for an assistance program, there is always the option of purchasing your medication from pharmacies located outside the US. While there are many pharmacies in many different countries that are willing to sell to US consumers, the best option is Canada. Why? The answer is twofold. First, buying from Canada is safer. The Canadian equivalent of the FDA, Health Canada, is stricter than the FDA (and other countries’ regulatory agencies) in its approval of new drugs. Second, Canadian pharmacies, on average, can sell medications for far less than pharmacies in the U.S. and other countries. They can do so for the following reasons:

• The Federal Patented Medicine Prices Review Board (PMPRB) regulates medications that are under patent. The PMRB dictates the maximum prices that can be charged in Canada for patented drugs.
• Health insurers, such as the provincial drug benefit plans, negotiate with the major pharmaceuticals to secure more favorable pricing on the medications that they cover.
• On average your $1 will buy you approximately $1.40 to $1.60 in medication from Canada.
• Health Canada is much quicker to approve generic versions of patented medication. The result is generic medications, which always cost less than patented medications, are available sooner in Canada.

Although there are many Canadian pharmacies, there are only a select few that you will want to buy from. Just like in the US, there are plenty of people willing to rip you off. And where your health is concerned, you do not want to take a chance. As a result, navigating the Canadian pharmacy option can be confusing and difficult. Luckily, as with the assistance programs, there are powerful tools available to help you find the pharmacy that is best for you.

It’s Simple to Start Saving

Just because you don’t have health insurance doesn’t mean that you can’t afford the medication that you need. The many assistance programs available to US citizens combined with the viable option of buying your prescription medication from Canada present the uninsured with the ability to purchase the medication that they need. Visit Rx Savings Guide to learn more about the tools available to help you afford your prescription medication.

The author, Garin Clark, is a co-founder of O2M Marketing. O2M is committed to delivering solutions to the marketplace that improve the lives of entrepreneurs while attempting to address some of the major social issues affecting us all.

As pointed out by *Jack Shapiro, an internationally-known healthcare marketing consultant “For the first nine months of this year, the U.S. imported $40 billion in pharmaceuticals and exported only $21 billion. In 2003, we imported $50 billion and exported $23 billion.” So what makes buying from your local U.S. based pharmacy any safer then purchasing from Mexico or Canada?

Many of today’s elderly (U.S.) cross the borders of Mexico and Canada in order to get their prescriptions filled at a huge discount. For some it has become a necessity because they simply can’t afford necessary drug treatments any other way.

But what about those who don’t live near the borders; how can they take advantage of these savings? Fact is there are a lot of prescription drugs that can be purchased online from international locations for a fraction of the cost people pay here in the United States. A good example of this is where many of today’s best known brand drugs can be found such as Viagra, Cialis, Levitra, Zocor, Zoloft, Propecia and more. However they not only offer name brand drugs at sharp discounts they also give seniors the opportunity to buy generic versions of most of these name brand drugs for savings that can reach up to 80% less then their name brand counterparts!

When a drug company first invents a drug (eg. Prozac) that company is the only one allowed to make that drug for a certain number of years (approximately 10 years in the US). After this time period, other companies are allowed to make the same drug. These drugs are called generics. The original drug (eg. Prozac) is called a brand name drug. Brand name drugs and their generics are IDENTICAL in terms of active ingredients. The generic pills may look different (because they are made by a different company) but inside is exactly the same active ingredient which works in exactly the same way. The only difference between brand name drugs and generic drugs is that generics are always less expensive.

Most all drugs found at www.rxmex.org require a prescription so this licensed pharmacy can fill most orders by having the purchaser fax them their prescription and the shipped order can be tracked online. Another benefit to ordering this way is that there is no tax to be paid and orders are shipped internationally.

While some headway has been made in the last year or so in regards to reducing prescription drug costs for seniors, for now it’s simply not enough for so many of our elderly. With the political clout of today’s drug companies who converge on Washington D.C. like vultures I’m not sure the costs will ever get to the point where it should be.