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Have you ever taken the drug Vioxx or celebrex? In September 2004 the drug manufacturer Merck decided to recall the product after long term data suggested a serious potential side effect.

This drug and others like it such as as ‘Celebrex’, ‘Bextra’ and ‘Arcoxia’ are part of a family of drugs known as “COX2 drugs” or “COX2 inhibitors”

They have been developed with, ironically, patient safety in mind.They are typically used in treatment of arthritis, though high dose vioxx was promoted for short term relief of acute muscular/skeletal pains.They were anti-inflammatory drugs.

The serious side effects were in connection with the heart suggesting risk of heart disease or heart attack.In medical circles it was referred to as “..adverse cardiovascular effects.”

There are other drugs used to treat inflammation that have been around for many years.YOu may have heard of products such as Advil or Nurofen which contain the ingredient Ibuprofen.Other older anti-inflammatory drugs include such brands as Voltarol or Naprosyn.

What’s the difference between these older drugs and the recent treatments know as “COX2 drugs”?

The newer drugs such as Arcoxia,Celebrex and Vioxx were designed to be much more specific in their mode action than old drugs like Ibuprofen.The idea was to limit the associated problems in long term treatment.

When we get older we all seem to get more sensitive to side effects of drugs.Often this is complicated even more by the fact that we may suffer from more than one problem or disease at the same time.

At this point we take more medication in the last five to ten years of our lives than in all the other years put together! Is it any wonder we might feel under the weather, a little off colour even?

You could have asthma and high blood pressure. Anxiety and lack of sleep every night. Panic attacks and depression.

If you take an anti-inflammatory drug for a given length of time, your doctor/physician will no doubt tell you about one major problem.

Ulceration of the stomach or intestines…..

It was hoped that the newer COX2 drugs would not cause this problem at all.Therefore it would avoid the risk of someone suffering internal bleeding which could become fatal.

The older you become the greater the risk of this occuring. It could be a slow blood loss or a sudden episode of an ulcer bleeding more profusely.

So when people got the signs of ulcers, they got treatment for an ulcer. Some would stop taking medication and others would take a maintenance dose to prevent ulcers coming back while continuing to take the old ibuprofen drugs for their arthritis.

It was hoped drugs like vioxx would stop this, but ulceration still remains a possibility. Doctors routinely consider offering anti ulcer drugs to reduce the probability of this happening.

So what is the all the recent fuss about ? Where did it all suddenly seem to unravel after all that hope and expectation ? A new long term study seemed to indicate some degree of risk to the heart some 18 months or so after starting treatment.

So if you took vioxx for a week or a couple of months, this potential problem did not appear.It has only been spotted after taking the medication for a longer period such as 18 months.

What can you do? Are there ways to reduce risks? This is something you need advice on as only your doctor will have your medical history.There is much to consider and such a problem can in some circumstances be minimised.

Of course if you smoke you increase the risk of stomach or intestinal ulceration if you also take anti-inflammatory drugs such as Ibuprofen.Why not quit instead?

If you take other medication for depression or anxiety then these drugs can increase the risk of bleeding with any anti-inflammatory drug being taken at the same time.

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Many people today realize the importance of keeping their blood pressure under control. Blood pressure monitors are now available for home use.

It’s a piece of medical equipment that can provide both you and your health care provider with an accurate measure of how your blood pressure is responding to diet, exercise and medication.

Many medical supplies outlets offer blood pressure monitors that are simple and easy to use.

For some people the thought of going to their Dr.’s office for a blood pressure reading is enough to send their pressure through the roof. That’s one of the advantages of having your own blood pressure cuff right in their own home. They can use the blood pressure cuff at their own convenience and get a more accurate reading.

High blood pressure can be caused by many different factors such as weight, diet and heredity. If you have an elevated pressure then having your own blood pressure monitors available can be very important.

The American Heart Association estimates that one of three Americans have have hypertension. And yet many of us don’t know what it is, why it’s dangerous, and what the treatment options are.

What Is Hypertension?

Hypertension is a fancy medical word for high blood pressure.

Your blood carries nutrients and oxygen to your body, and picks up waste like carbon dioxide. The heart pumps the blood through “pipes” - blood vessels called arteries- and the blood returns to the heart through veins.

Blood pressure is the “push” of blood against the walls of the arteries. It is a good thing to have blood pressure - if blood pressure is zero, it means there’s no blood moving through the arteries! But like the water pipes in a house, if the blood is being pushed too hard against the walls of the vessels, they might be damaged. Extra pressure can also contribute to creating blood clots that block needed blood supply to the brain.

Hypertension can lead to dangerous conditions including heart failure (when the heart has to work too hard just to get the blood moving around the body), stroke (interference with the blood flow in the brain), and kidney disease, to name a few.

How Do I know If I’m At Risk?

While having a family history of hypertension may increase your risk for hypertension, not all people with hypertension have family members with it. Hypertension is generally “asymptomatic” - most people don’t have symptoms as they develop it - so checking your blood pressure should be a part of regular healthcare.

How Is High Blood Pressure Diagnosed?

When your blood pressure is taken at a health clinic or doctor’s office, the result is a mysterious number like this:

120 / 80

The first/top number is called the “systolic” (sis-tall-ick) blood pressure; the second/bottom, the diastolic (dye-as-tall-ick) pressure. The American Heart association recommends that the top number in adults should be no higher than 120 and the bottom no higher than 80 (children have different ranges of healthy blood pressure for different age groups - ask your pediatrician if you’re concerned). If your systolic pressure is between 140 to 159 and/or your diastolic pressure is between 90 and 99, that’s considered mild hypertension. Moderate to severe hypertension includes systolic pressures over 160 and/or diastolic over 100.

What Are My Treatment Options?

Treatment depends on the severity of the high blood pressure. Keep in mind that a very stressful day can increase your blood pressure readings, as (for some people) can a trip to your doctor’s office. So if your blood pressure reading is on the border between healthy and hypertensive, you may need to make a return visit.

If you have a pre-hypertensive blood pressure after a repeat check, your doctor or nurse practitioner may recommend a trial of lifestyle changes that can help lower blood pressure including:

-exercise

-a lower-salt diet

-increased intake of potassium

-weight loss

-moderation of alcohol consumption

-stress reduction

However, if you have mild to severe hypertension (Stage 1 or 2), or if you have pre-hypertension in combination with conditions like heart disease, kidney disease, or diabetes, your health care provider may prescribe medications.

There are many different hypertension medications. They don’t all work the same way, and different ones work differently for different people, so your provider will probably have you check in to make sure the medication first prescribed is working for you. Sometimes two medications can compliment each other, so your healthcare provider may prescribe two kinds.

Once medication has been prescribed sit down with your health care provider or pharmacist and a list of all the medications you take (including over the counter medications) to make sure that there are no harmful interactions between them and tyour blood pressure medicines. In addition, keep in mind that most blood pressure medications have side effects; ask your healthcare provider to write down likely side effects for you, noting side effects and symptoms that indicate that you should come in to have your dose changed.

Most importantly, medication is not enough! Make sure to modify your lifestyle to help the medications do a good job. “High Blood Pressure” Nidus Information Services, 2004

“Percentage of adults aged ≥20 who were ever told they had high blood pressure” Morbidity and Mortality Weekly Reports, Center for Disease Control, Behavioral Risk Factor Surveillance System, volume 51, issue 21, 2002

Why is your blood pressure low?

As a doctor with an interest in the subject, I’m often asked if a low blood pressure is normal or if such a reading indicates some abnormal process in the body? In fact ? it can be difficult to precisely define what we mean by low blood pressure. It all really depends on what’s normal for you as an individual.

If 1000 people had their blood pressure measured then we might expect to find a spread of readings. These might range from as high as 200 / 120 down to 80 / 50 with most people clustering around a level of around 130 / 85. Most of these people would have no symptoms of any kind ? no matter what their blood pressure reading actually was. Even those with obviously low blood pressure would be free of any symptoms in most cases.

The answer to whether it is normal or abnormal to have a low blood pressure depends on what your own typical or average blood pressure reading is.

Here’s an example of when it’s normal to have low blood pressure.

If, for the whole of your life, you’ve always had blood pressure readings of around 90 / 50 - then without doubt you have “low blood pressure” but there is truly nothing wrong with you or with your blood pressure reading. You should be pleased that your risk of stroke or heart attack will be much less than many others. You’re not likely to experience any symptoms from your “low blood pressure.” Putting it simply - your blood pressure is normal for you and needs no investigation or treatment. This kind of “normal low blood pressure” will not cause you any symptoms and will need no treatment. It’s just part of you and how your system works.

So, when might low blood pressure be an abnormal finding?

If your blood pressure is usually around 130 / 80 and suddenly or gradually drops to a level around 90 / 50 then it’s very likely that you’ll become aware of symptoms related to this change. As in the above example you have “low blood pressure” but in this instance it is not normal for you to have readings this low. You may need to see your doctor for tests because it’s quite likely that some other disease or perhaps a medication has caused your blood pressure to drop. Someone who develops low blood pressure like this will often experience symptoms such as those listed below.

The symptoms of an abnormally low blood pressure can include:

Feeling light headed, feeling dizzy, being tired or feeling fatigue on exertion, fainting, transient blurring of vision, or transient confusion. All of these low blood pressure symptoms will resolve if the blood pressure returns to normal.

The following are among the many possible causes of low blood pressure when it is abnormally low:

Medications for anxiety, medications for blood pressure, heart medications, diuretics or “water tablets” and some anti-depressant medications. Other medication related causes are painkillers and alcohol ? particularly if these two are mixed together!

Non medication causes of include dehydration, heart disease and heart valve disease, recent heart attack, changes in heart rhythm, bacterial infection in the system, kidney diseases, diabetes mellitus and haemorrhage or bleeding.

As you can see, the above list of the causes of low blood pressure is extensive and you should consult with your doctor if you are concerned in any way. Above all ? don’t try to diagnose your own condition ? seek help if you are worried. Low blood pressure is not likely to do you any serious harm but it can leave you feeling pretty miserable.

Resperate is natural and powerful and it puts you in control of your blood pressure.

Resperate is a new device and is revolutionising the nature of blood pressure treatment. Blood pressure sufferers throughout the world are catching on to the amazing potential of Resperate and their lives are changing because of it. Those with high blood pressure are able to reduce or stop their blood pressure medication and some with low blood pressure are able to get rid of low blood pressure symptoms.

Resperate uses biofeedback to control your blood pressure and the idea behind the Resperate device is not new.

Biofeedback has been used for decades to change internal body functions such as heart rate, bowel speed and adrenaline release. Yoga students and martial arts experts say they can control blood pressure by focus and medidation. Resperate brings that ability to us all. If you learn to use Resperate then you might not need drugs or blood pressure medications. At the least, you will be able to reduce the number of tablets you need to take each day.

So how does Resperate work?

Well, in very simple terms, the Resperate device teaches you to control your own blood pressure. If you devote about twenty minutes a day to practicing with the machine you’ll quickly notice a big difference. And it really does work - not just in lowering blood pressure but in reducing overall stress and tension levels. High blood pressure isn’t known as “Hyper - Tension” for nothing!

The makers say that Resperate takes around eight weeks to have its effect, but some research studies show that it acts more quickly than that. It works by bringing blood pressure control to a conscious level and, because of that, you can use Resperate to reduce high blood pressure or to treat low blood pressure.

If you have low blood pressure problems then Resperate can truly be a godsend because there are few other effective treatments available.

Research studies have shown that Resperate can reduce blood pressure by about twenty points on the scale. For most patients this is very significant and will benefit their health enormously. Reducing medication will also make most blood pressure patients feel better because many effective blood pressure tablets have problematic side effects.

Resperate retails for around three hundred dollars. As a one off cost it’s not cheap but in the longer term it may save you many times that amount.

Resperate works. If you have high blood pressure or low blood pressure then you really ought to take a close look at what it has to offer.

High blood pressure or what is medically known as hypertension affect millions of Americans. In fact, about 80 million people in the US have high blood pressure and what is more terrifying is the fact that some of these people are not even aware that they have high blood pressures. This is why hypertension has become known as the silent killer because unless you have your blood pressures checked regularly, you have no way of knowing that you already have it until it is already much too high up the scale.

High blood pressure will often manifests itself through headaches, dizziness and nose bleeds. Some people will also feel pain at the back of their necks when they wake up in the morning. Hypertension is not really life-threatening per se as it is not a disease. The level of blood pressure, however, is a risk factor to heart disease and will increase one’s predisposition to heart attacks. This is especially true with people who are over 35 years old and those who are much much older.

Because it is a condition and not a disease, people can do a lot to prevent hypertension from settling in. Most doctors recommend a change in the diet and a major lifestyle change.

Diet is perhaps the primary lifestyle change that people should look into when dealing with high blood pressure. Excessive eating of fatty foods that cannot be easily digested can cause a lot of problems. Obese individuals are also more likely to develop hypertension not only because of the fat content in their bodies but also the constriction that these fats produce in the body. This constriction can affect blood circulation and heart function, which may lead to a full-blown heart attack.

Another advice that doctors give to individuals concerned with their blood pressure is to have regular exercise regimen that would help lower their blood pressure. Activities such as running and jogging, cycling and swimming as well as other sports can decrease blood pressure. Doctors recommend that people exercise and do these sports activities for about 30 to 45 minutes a day and they will find their blood pressures significantly lowered.

Alcohol, for instance, increase the prevalence of hypertension when it is taken in excess. The term excess here will refer to over two drinks per day. Studies have actually shown a direct relationship between these two factors when the drinking exceeds five glasses each day. A drink here refers to a can of beer, a glass of wine or a jigger of liquor. There are people however who have low tolerance with alcohol. It is best to stop drinking if you find your blood pressure going up or if you feel nauseous already.

Smoking is also one of the things that a person should avoid when trying to either lower blood pressure or to prevent it from going up. Besides the complications that it poses to the lungs and the vascular system, smoking also increases the risk for heart disease. This is because the nicotine in cigarettes and tobaccos can constrict one’s blood vessels, causing the heart to beat faster.

Elderly people are also asked to avoid excessive coffee drinking. In a study conducted, it was found that five cups of coffee per day can mildly increase the blood pressure. The combination of coffee drinking with smoking increases the risk all the more.